Minor Histocompatibility Antigens

From the Laboratory to the Clinic
With the widespread application of solid tissue and bone marrow transplantation as a treatment for an array of life threatening disorders, there is a pressing need for clinicians and experimentalists to understand the basis of immunological rejection of tissue transplants
With the widespread application of solid tissue and bone marrow transplantation as a treatment for an array of life threatening disorders, there is a pressing need for clinicians and experimentalists to understand the basis of immunological rejection of tissue transplants. While much previous work focuses on characterization of antigens encoded by the major histocompatibility complex (MHC) in this process, the many histocompatibility (H) antigens encoded outside of the MHC, the so-called minor H antigens, have only recently been identified at the molecular level. This easily readable but comprehensive text is the first to put together i